Precision RNA Medicine Core
Harvard Medical School Initiative for RNA Medicine
Beth Israel Deaconess Medical Center
The Precision RNA Medicine Core (PRM) provides state-of-the-art Spatial Tissue Profiling, Single Cell, RNA detection, quantification, delivery, and Next Generation Sequencing. It provides investigators not only the ability to identify new targets and biomarkers, but also the capability to validate them as relevant to the disease they are studying.
PRM equipment and Services are available not only to BIDMC and HMS-affiliated Clinicians and Faculty but also Academics, startups and industry based within the US and abroad.
The Precision RNA Medicine Core is comprised of 4 Units
Spatial Technologies Unit
Provides comprehensive spatial tissue profiling, single cell profiling
Detection Unit
Hosts highly sensitive and selective qRTPCR technology from MiRXES to quantify non-coding RNAs in minimal sample volumes.
Bioinformatics Unit
Specializes in in silico methods for analysis and prioritization of non-coding RNAs and variants in basic, applied, and translational research.
Delivery Unit
Performs delivery of RNA via nanoparticle packaging both in vitro and in vivo using the NanoAssemblr Spark, Ignite, and Blaze from Precision NanoSystems.
Team
Dr. Frank Slack (Academic Co-director), Dr. Winston Hide (AcadmicDirector), Dr. Ioannis Vlachos (Academic Director STU and Bioinformatics),
Leinal Sejour (Analyst, Bioinformatics Unit)
Dr. Jan Heng (Academic Director, Detection Unit), Madison Uyemura (Director, Delivery Unit)
We are located in the Dana Building at the East Campus of Beth Israel Deaconess Medical Center in Longwood.
330 Brookline Ave.
Dana Building
Beth Israel Deaconess Medical Center
Boston, 02115 MA, USA
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