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Precision RNA Medicine Core

Harvard Medical School Initiative for RNA Medicine

Beth Israel Deaconess Medical Center

The Precision RNA Medicine Core (PRM) provides state-of-the-art Spatial Tissue ProfilingSingle Cell, RNA detection, quantification, delivery, and Next Generation Sequencing. It provides investigators not only the ability to identify new targets and biomarkers, but also the capability to validate them as relevant to the disease they are studying.

PRM equipment and Services are available not only to BIDMC and HMS-affiliated Clinicians and Faculty but also Academics, startups and industry based within the US and abroad.

The Precision RNA Medicine Core is comprised of 4 Units

Spatial Technologies Unit

 

Provides comprehensive spatial tissue profiling, single cell profiling

 

 

Detection Unit

 

Hosts highly sensitive and selective qRTPCR technology from MiRXES to quantify non-coding RNAs in minimal sample volumes.

 

Bioinformatics Unit

 

Specializes in in silico methods for analysis and prioritization of non-coding RNAs and variants in basic, applied, and translational research.

 

Delivery Unit

 

Performs delivery of RNA via nanoparticle packaging both in vitro and in vivo using the NanoAssemblr Spark, Ignite+, and Blaze from Precision NanoSystems.

 

Team

Dr. Frank Slack (Academic Co-director), Dr. Winston Hide (Academic Director), Dr. Ioannis Vlachos (Academic Director STU and Bioinformatics), Dr. Jan Heng (Academic Director, Detection Unit)

 

 

Leinal Sejour (Analyst, Bioinformatics Unit), Ashton Black (Lead Technician, Delivery Unit)

We are located in the Dana Building at the East Campus of Beth Israel Deaconess Medical Center in Longwood.

330 Brookline Ave.
Dana Building
Beth Israel Deaconess Medical Center
Boston, 02115 MA, USA
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